Applied Research Physics Life Sciences DOI: 10.54546/NaturalSciRev.100303 Characterization of micro-SPECT system based on Timepix detector In this work, the characteristics of a prototype SPECT system based on the Timepix readout chip, with a MURA-type encoding mask, were evaluated. The setup has a small FoV and can be used in preclinical studies of drugs on small laboratory animals. Despite many existing test protocols developed and described in pertinent documents of national standard bodies and IAEA recommendations, they are not suitable for microtomographic systems based on semiconductor pixel detectors due to different detector technology, high spatial resolution and small area of interest. To measure their characteristics, special phantoms were developed, with a small “hot region”. Such micro-SPECT parameters as spatial resolution, contrast, linearity, and system efficiency were studied using 99m Tc source. The detector calibration and data preprocessing are described. V. Rozhkov, I. Hernа́ndez, A. Leyva, A. Zhemchugov 17.06.2025
