Abstract
With the emergence of the FLASH irradiation method in proton therapy, the need for high-current accelerators has grown significantly. Addressing this demand, the Joint Institute for Nuclear Research (JINR) has initiated the development of the MSC230, a compact isochronous cyclotron designed to produce high-intensity proton beams at 230 MeV for advanced biomedical research. Currently, the technical design of the cyclotron is in progress at D. V. Efremov Institute of Electrophysical Apparatus. Modifications during this phase often necessitate additional calculations, resulting in updates to the magnetic field configuration and beam dynamics. This article details the design methodologies and computational tools employed in the MSC230 project.
References
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[3]https://www.appliedradiology.com/articles/varian-first-patient-treated-in-fast-01-flash-therapy-trial
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[5]http://www.mevion.com/products/mevion-s250-proton-therapy-system
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[9] D. Vandeplasche et al., Extracted beams from IBA’s C235, in: Proceedings of Particle AcceleratorConference, Vol. 1, 1997.
[10] O. Karamyshev et al., Research and development of the SC230 superconducting cyclotron forproton therapy, Physics of Particles and Nuclei Letters 18 (1) (2021) 63–74.
[11] K. S. Bunyatov et al., Progress in design of MSC230 superconducting cyclotron for proton therapy,23rd International Conference on Cyclotrons and Their Applications (CYC2022), Beijing, China,THPO012, p. 327.
[12] O. V. Karamyshev, Beam dynamics in a new 230 MeV cyclotron, 23rd International Conferenceon Cyclotrons and Their Applications (CYC2022), Beijing, China, WEPO003, p. 208.
[13] H. G. Khodzhibagiyan et al., Development of superconducting accelerator magnets at JINR,Natural Science Review 1 (6) (2024).
[14] O. Karamyshev et al., CORD (Closed Orbit Dynamics): A new field map evaluation tool forcyclotron particle dynamics, Physics of Particles and Nuclei Letters 18 (4) (2021) 481–487.
[15] M. Palnikov, Calculation of pressure distribution in the vacuum chamber of the MSC-230 cy-clotron, Master’s Thesis, Dubna University, 2024 (in Russian).
[16] D. Popov et al., Beam extraction simulation and magnetic channels’ design for MSC230 cy-clotron, 23rd International Conference on Cyclotrons and Their Applications, 2022, Beijing, China,THAO02.
[2] S. Jolly, Y. Owen, M. Shipper, C. Welsch, Technical challenges for FLASH proton therapy, PhysicaMedica 78 (2020) 71–82.
[3]https://www.appliedradiology.com/articles/varian-first-patient-treated-in-fast-01-flash-therapy-trial
[4] S. V. Akulinichev et al., Potential of proton FLASH therapy on the accelerator of the Institutefor Nuclear Research of the Russian Academy of Sciences, Izvestiya RAN. Series Physics, 84 (11)(2020) 1544–1548 (in Russian).
[5]http://www.mevion.com/products/mevion-s250-proton-therapy-system
[6] G. Karamysheva et al., Present status of the SC202 superconducting cyclotron project, VIIIthInternational Particle Accelerator Conference (IPAC 2017), Copenhagen, Denmark, THPVA120.
[7] H. Tsutsui et al. Current status of Sumitomo’s superconducting cyclotron development for protontherapy, Cyclotrons 2019, Cape Town, FRA02, pp. 340–343.
[8] J. Schippers, R. D ̈olling, J. Duppich, G. Goitein, M. Jermann, A. Mezger et al., The SC cyclotronand beam lines of PSI’s new proton therapy facility PROSCAN, Nuclear Instruments and MethodsB 261 (2007) 773.
[9] D. Vandeplasche et al., Extracted beams from IBA’s C235, in: Proceedings of Particle AcceleratorConference, Vol. 1, 1997.
[10] O. Karamyshev et al., Research and development of the SC230 superconducting cyclotron forproton therapy, Physics of Particles and Nuclei Letters 18 (1) (2021) 63–74.
[11] K. S. Bunyatov et al., Progress in design of MSC230 superconducting cyclotron for proton therapy,23rd International Conference on Cyclotrons and Their Applications (CYC2022), Beijing, China,THPO012, p. 327.
[12] O. V. Karamyshev, Beam dynamics in a new 230 MeV cyclotron, 23rd International Conferenceon Cyclotrons and Their Applications (CYC2022), Beijing, China, WEPO003, p. 208.
[13] H. G. Khodzhibagiyan et al., Development of superconducting accelerator magnets at JINR,Natural Science Review 1 (6) (2024).
[14] O. Karamyshev et al., CORD (Closed Orbit Dynamics): A new field map evaluation tool forcyclotron particle dynamics, Physics of Particles and Nuclei Letters 18 (4) (2021) 481–487.
[15] M. Palnikov, Calculation of pressure distribution in the vacuum chamber of the MSC-230 cy-clotron, Master’s Thesis, Dubna University, 2024 (in Russian).
[16] D. Popov et al., Beam extraction simulation and magnetic channels’ design for MSC230 cy-clotron, 23rd International Conference on Cyclotrons and Their Applications, 2022, Beijing, China,THAO02.