Historical / Anniversary Reviews
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Historical / Anniversary Reviews

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Life Sciences Historical / Anniversary Reviews
DOI: 10.54546/NaturalSciRev.100804

The history of the development and use of neutron activation analysis in medical and biological research in the USSR and Russia

The year 2026 marks two significant anniversaries in the history of nuclear and analytical science: 100 years since the development of the tracer method, which laid the foundation for nuclear medicine, and 90 years since the discovery of neutron activation analysis (NAA), both associated with the pioneering work of György de Hevesy. To commemorate these milestones, this review examines the development and application of NAA in clinical and experimental medicine in the Soviet Union and Russia. Particular attention is given to the research centers that employed NAA, the biological materials and medical problems investigated, and the major scientific advances achieved. The review traces the development of more than 20 research nuclear reactors in the USSR and the establishment of specialized research units that applied NAA to biomedical problems. The studies are presented chronologically, covering investigations of chemical elements in biological fluids, tissues, organs, cells, and biomolecules under normal and pathological conditions, as well as applications involving stable isotope tracers, drug and contrast-agent pharmacokinetics, nanoparticles, and unique in vivo measurements. The review demonstrates that NAA provided important advantages, including multi-element analysis, high sensitivity, and the possibility of investigating trace elements in biological systems without extensive sample preparation. These capabilities contributed to advances in fundamental biomedical research and to the development of new diagnostic approaches. The historical record highlights the substantial contribution of Soviet and Russian scientists to the application of NAA in medicine and provides a basis for assessing its continuing scientific significance.
V. Zaichick, M. Frontasyeva, I. Zinicovscaia
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Historical / Anniversary Reviews 70th anniversary of JINR
DOI: 10.54546/NaturalSciRev.200604

Statistical field theory of forced magnetohydrodynamic turbulence

We review the results of applying the statistical field-theoretic approach to the problem of fully developed turbulence in nonrelativistic three-dimensional magnetohydrodynamics (MHD), which have been obtained over the past forty years. The review covers both general aspects of the physics of MHD turbulence and the necessary mathematical machinery of statistical field theory, including elements of renormalization theory and the renormalization-group (RG) method. The approach is illustrated using a stochastic model of stationary, locally homogeneous, fully developed three-dimensional MHD turbulence in the general case of a medium with broken spatial parity (helical MHD). In this model, RG techniques make it possible to establish the existence of several infrared-stable scaling regimes and to calculate the critical dimensions of various composite operators, the infrared asymptotics of correlation functions, and the amplitude factors in scaling laws, as well as to incorporate the effects of compressibility, anisotropy, etc. For an important class of helical MHD systems, the field-theoretic approach provides an elegant formulation of the fundamental problem of large-scale turbulent dynamo action — namely, the generation of a large-scale magnetic field ⟨ b ⟩ = B (where b denotes magnetic fluctuations) at the expense of the energy of turbulent fluctuations — via the decay of the initial unstable vacuum state ⟨ b ⟩ = 0 as a result of dynamical spontaneous symmetry breaking in the spirit of the Coleman-Weinberg mechanism, followed by stabilization of the theory in the vicinity of the new ground state ⟨ b ⟩ = B (the dynamo regime). The field-theoretic formulation we developed, together with a generalization of the standard Feynman diagrammatic technique to the dynamo regime, not only makes it possible to treat within a unified framework the existing theoretical approaches to helical magnetohydrodynamics (kinematic MHD, large-scale dynamo theory), but also extends the RG formalism to the dynamo regime, which — unlike closure procedures still common in dynamo theory — is particularly well suited for studying statistically stationary turbulent states. The richness of MHD physics in the dynamo regime is illustrated both in the emergence of new effects (Goldstone-type corrections to Alfvén waves, anisotropic corrections associated with the transport of the large-scale field) and in the theoretically predicted strong dependence of the magnetic energy-spectrum slope on the degree of mirror-symmetry breaking.
M. Hnatič, T. Lučivjanský, L. Mižišin, Yu. Molotkov, A. Ovsiannikov