The Continuous analogue of Newton's method (CANM), developed at JINR since the 1970s, is one of most important areas of research at Laboratory of Computing Techniques (LCTA) -- Meshcheryakov Laboratory of Information Technologies (MLIT). CANM and its generalization are powerful tools for the effective numerical solution of nonlinear problems within a wide range of complex physical systems studied at JINR. This review article provides a general framework for the CANM-based approach, the main stages in the development and applications of CANM for solving various types of nonlinear problems that have been on the agenda in different years. The results of the development and application of CANM-based iterative methods, obtained over the past 20 years, are presented in more detail.